Heptaibin, a novel antifungal peptaibol antibiotic from Emericellopsis sp. BAUA8289.

نویسندگان

  • D Ishiyama
  • T Satou
  • H Senda
  • T Fujimaki
  • R Honda
  • S Kanazawa
چکیده

Institute of Biotechnology Applied to Soil Eumycetes, 241 , Kariwano, Nishisenboku, Senboku, Akita 019-21 12, Japan a Development Research Laboratories, Kaken Pharmaceutical Co., Ltd., 301 Gensuke, Fujieda, Shizuoka 426-8646, Japan b Development Research Laboratories, Kaken Pharmaceutical Co., Ltd., 1 4 Minamikawaratyou, Shinomiya, Yamashina, Kyoto 607-8042, Japan c Research Laboratory, Agrochemicals and Animal Health Products Department, Kaken Pharmaceutical Co., Ltd., 301 Gensuke, Fujieda, Shizuoka 426-8646, Japan

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Isolation and structure of peptaibolin, a new peptaibol from Sepedonium strains.

peptaibols in microbial culture extracts3~5). Here we report the isolation and structure elucidation of peptaibolin (1, Fig. 1) as an unusual representative of the peptaibol family of lipophilic antibiotics. 1 was disclosed in two fungal strains, Sepedonium sp. HKI-0117 and Sepedonium ampullosporum HKI-0053 coproducing the neuroleptic peptaibol-type antibiotic ampullosporin5). In contrast to th...

متن کامل

Formamicin, a novel antifungal antibiotic produced by a strain of Saccharothrix sp. II. Structure elucidation of formamicin.

A novel antifungal antibiotic, formamicin, was isolated from the culture broth of Saccharothrix sp. MK27-91F2. The absolute structure of formamicin was determinated by spectroscopic and X-ray crystallographic analysis and degradation study.

متن کامل

Identification of peptaibols from Trichoderma virens and cloning of a peptaibol synthetase.

The fungus Trichoderma virens is a ubiquitous soil saprophyte that has been applied as a biological control agent to protect plants from fungal pathogens. One mechanism of biocontrol is mycoparasitism, and T. virens produces antifungal compounds to assist in killing its fungal targets. Peptide synthetases produce a wide variety of peptide secondary metabolites in bacteria and fungi. Many of the...

متن کامل

YM-47522, a novel antifungal antibiotic produced by Bacillus sp. I. Taxonomy, fermentation, isolation and biological properties.

YM-47522, a novel antibiotic, was isolated from the culture broth of Bacillus sp. YL-03709B. The antibiotic was purified by centrifugal partition chromatography and ODS column chromatography. It exhibited potent in vitro antifungal activity especially against Rhodotorula acuta and Pichia angusta (MIC: 0.05 and 0.75 microgram/ml, respectively). It also showed moderate or weak antifungal activity...

متن کامل

YM-47522, a novel antifungal antibiotic produced by Bacillus sp. II. Structure and relative stereochemistry.

YM-47522 (1) was isolated from the fermentation broth of Bacillus sp. YL-03709B as an antifungal antibiotic. The structure of 1 was elucidated by spectroscopic analyses. YM-47522 (1) consisted of C13 carboxylic acid amide and cinnamate moieties. The relative stereochemistry was also proposed on the basis of chemical transformation into a 1,3-diol acetonide and its NMR data.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of antibiotics

دوره 53 7  شماره 

صفحات  -

تاریخ انتشار 2000